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KMID : 0357920050390050351
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Korean Journal of Pathology
2005 Volume.39 No. 5 p.351 ~ p.355
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Benign Histiocytoma of the Lung : A Case Report
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Chung Myoung-Ja
Son Hyun-Jin
Kim Min-Ho
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Abstract
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Histiocytomas have rarely been reported in the lungs. We report an unusual benign pulmonary histiocytoma in a 45-year-old man and discuss the differential diagnosis. Chest CT showed a well-defined solitary pulmonary nodule of approximately 3 cm in size in the posterobasal segment of the right lower lobe. Posterolateral thoracotomy and wedge resection was performed. Gross examination revealed a mass, measuring 2.2×2.1 cm that had a circumscribed margin within the lung parenchyma. Microscopically, the tumor was entirely composed of large polygonal to round cells with a few chronic inflammatory cells. These tumor cells contained abundant cytoplasm which was either granular, eosinophilic or foamy. Immunohistochemically, these cells were diffusely positive for CD68 and focally positive for 1-antitrypsin, but negative for cytokeratin, vimentin, and smooth muscle actin.
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KEYWORD
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Histiocytoma, Lung
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